Status:
UNKNOWN
Analysis of Biliary Microbiota in Hepatobiliopancreatic Diseases Compared to Healthy People [MICROBILIO]
Lead Sponsor:
University of Sao Paulo
Conditions:
Pancreatic Diseases
Microbiota
Eligibility:
All Genders
18+ years
Brief Summary
The performance of the microbiota is observed in all clinical and pathological stages of carcinogenesis, since its development, diagnosis and treatment, including prognosis and survival. However, it w...
Eligibility Criteria
Inclusion
- Endoscopic retrograde cholangiopancreatography (ERCP) candidates (case group)
- Patients over 18 years old complete
- Patients previously scheduled for ERCP
- Cannulation of the bile duct, via the transpapillary route, with the aid of a papillotome with an end kept sterile until contact with the papilla
- Liver transplant living-donor (control group)
- Patients over 18 years old up to 55 years
- Previously selected patients with scheduled surgery
- BMI: 18 kg / m² to 28 kg / m²
- Blood typing identical to the recipient
- Absence of significant medical, psychiatric problems or previous abdominal surgery
- Normal laboratory tests: liver function tests, blood count, coagulogram, pregnancy test and serology for hepatitis B, C and HIV
- Normal imaging exams: CT of the abdomen and pelvis with liver volume (remaining volume - 30-40% of the total liver volume), MRI with cholangioresonance
Exclusion
- ERCP candidates (case group)
- Use of antibiotics during ERCP or in the last 2 months prior to the procedure
- Emergency ERCP
- Pregnancy
- Uncorrected coagulopathy
- Liver transplant living-donor (control group)
- Use of antibiotics in the last 2 months prior to the procedure
- Pregnancy
- Uncorrected coagulopathy
Key Trial Info
Start Date :
June 3 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
January 16 2024
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04391426
Start Date
June 3 2021
End Date
January 16 2024
Last Update
September 28 2021
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Sao Paulo School of Medicine
São Paulo, Brazil, 05403-000