Status:
COMPLETED
Cerebral and Circulatory Effects of Neonatal Volume Targeted Ventilation
Lead Sponsor:
Poznan University of Medical Sciences
Conditions:
Respiratory Distress Syndrome, Newborn
Respiratory Failure
Eligibility:
All Genders
24-27 years
Phase:
NA
Brief Summary
The aim of the study was to assess the effect of volume targeted vs. pressure-controlled mechanical ventilation (MV) on circulatory parameters and cerebral oxygenation in the extremely preterm infants...
Detailed Description
Prospective, cross-over trial enrolling neonates \<28 weeks' gestation requiring MV. Patients were ventilated for 3 hours with pressure controlled assist-control (PC-AC) mode, followed by 3-hours of v...
Eligibility Criteria
Inclusion
- premature infants born \<28 weeks of gestation
- respiratory failure in the course of respiratory distress syndrome requiring mechanical ventilation
- stable condition with pH (acidity of blood)\> 7.2 and pCO2 (carbon dioxide partial pressure) \<60 mmHg in the blood gas analysis
- no identified genetic syndromes and serious congenital malformations
Exclusion
- lack of written consent of patients' parents
Key Trial Info
Start Date :
August 1 2017
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 30 2018
Estimated Enrollment :
25 Patients enrolled
Trial Details
Trial ID
NCT04391634
Start Date
August 1 2017
End Date
May 30 2018
Last Update
May 21 2020
Active Locations (1)
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1
Department of Neonatology at Poznań University of Medical Sciences
Poznan, Poland, 60-535