Status:
COMPLETED
Study of Bone Mineral Density and Trabecular Bone Score in Patients With Ankylosing Spondylitis
Lead Sponsor:
Mansoura University
Conditions:
AS
Eligibility:
MALE
22-64 years
Phase:
NA
Brief Summary
Osteoporosis is a common complication of AS even in the early stages of disease. Yet, AS is also characterized by new bone growth that leads to syndesmophytes formation and subsequent vertebral ankylo...
Detailed Description
Accordingly, previously-published studies have demonstrated large discrepancies in the reported incidence of osteoporosis, based on measurement of bone mineral density (BMD), in patients with AS rangi...
Eligibility Criteria
Inclusion
- A total of 40 consecutive male AS patients were invited to participate in this study. Patients were recruited from Outpatient Clinic of Rheumatology, Mansoura University Hospital, between January and September 2019. AS was diagnosed according to modified New York criteria. During the same period, 40 age-matched healthy males were invited to participate in the study as a control group.
Exclusion
- patients or controls with thyroid or parathyroid disorders, presence of chronic renal or liver disease, and use of any medication that could potentially interfere with bone metabolism including bisphosphonates, teriparatide, anticonvulsants, anticoagulants, calcium and corticosteroids. None of the participants was using vitamin D supplements.
Key Trial Info
Start Date :
January 2 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 15 2020
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT04392596
Start Date
January 2 2019
End Date
January 15 2020
Last Update
May 19 2020
Active Locations (1)
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1
Mansoura University Hospital
Al Mansurah, Dakahlia Governorate, Egypt, 35516