Status:
TERMINATED
Dexamethasone for COVID-19 Related ARDS: a Multicenter, Randomized Clinical Trial
Lead Sponsor:
Centro de Educación Medica e Investigaciones Clínicas Norberto Quirno
Conditions:
Respiratory Distress Syndrome, Adult
Covid-19
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
There is compelling data indicating that there is an excessive inflammatory response in some patients with COVID-19 leading them to develop ARDS that can be severe with a very poor prognosis. Many of ...
Eligibility Criteria
Inclusion
- ARDS according to Berlin's definition
- PCR confirmed COVID-19
- Length of mechanical ventilation less or equal to 72 hours
Exclusion
- Pregnancy or breast-feeding women
- Terminal illness with very poor prognosis according to the investigator judgement
- Therapeutic limitation
- Known immunocompromised condition
- Chronic use of systemic corticosteroids
- Participation in another randomized crinical trial
- More than 5 days of treatment of low dose dexamethasone for COVID-19
- Abscence of informed consent
- Active participation in other randomized clinical trial
Key Trial Info
Start Date :
May 21 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 21 2021
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04395105
Start Date
May 21 2020
End Date
May 21 2021
Last Update
June 2 2021
Active Locations (4)
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1
Clínica Bazterrica
Buenos Aires, Argentina, 1425
2
Hospital Universitario Sede Pombo - IUC CEMIC
Buenos Aires, Argentina, 1425
3
Sanatorio Sagrado Corazon
Buenos Aires, Argentina
4
Hospital Universitario Sede Saaveda - IUC CEMIC
CABA, Argentina, 1431