Status:
TERMINATED
Helmet CPAP Versus HFNC in COVID-19
Lead Sponsor:
Lund University
Collaborating Sponsors:
Region Skane
Conditions:
COVID
Acute Hypoxemic Respiratory Failure
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
We aim to investigate whether the use of Continuous Positive Airway Pressure using a Helmet device (Helmet CPAP) will increase the number of days alive and free of ventilator within 28 days compared t...
Detailed Description
A detailed description can be found in the study protocol published in Trials in Dec 2020: Tverring, J., Åkesson, A. \& Nielsen, N. Helmet continuous positive airway pressure versus high-flow nasal c...
Eligibility Criteria
Inclusion
- Inclusion Criteria (all of the following):
- Age ≥ 18 years
- Sars-Cov-2 found in the upper or lower respiratory tract by PCR during the current disease episode
- Peripheral oxygen saturation (SpO2) \< 92 % despite conventional low-flow oxygen therapy of at least 6 L /min for at least 15 min
- A decision to initiate HFNC or Helmet CPAP by the attending ward physician
- The patient has given written informed consent to participate.
- Exclusion Criteria (any of the following):
- Need for direct admission to the intensive care unit for mechanical ventilation
- Unconsciousness or drowsiness
- Pneumothorax
- Carbon dioxide pressure (pCO2) \> 6 kPa in venous blood gas (VBG)
- Underlying chronic obstructive pulmonary disease stage III-IV
- A decision not to participate
- Inability to comprehend the study content and give informed consent
Exclusion
Key Trial Info
Start Date :
June 3 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 12 2021
Estimated Enrollment :
2 Patients enrolled
Trial Details
Trial ID
NCT04395807
Start Date
June 3 2020
End Date
April 12 2021
Last Update
April 15 2021
Active Locations (1)
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1
Helsingborg's Hospital
Helsingborg, Region Skane, Sweden, 252 23