Status:

UNKNOWN

Conventional Photodynamic Therapy vs. Painless Photodynamic Therapy for Actinic Keratosis

Lead Sponsor:

Shanghai Dermatology Hospital

Conditions:

Actinic Keratosis

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This study is being done to compare a new, continuous illumination and short Incubation time regimen of aminolevulinic acid photodynamic therapy#ALA-PDT) to a conventional regimen for treatment of Act...

Detailed Description

This study is being done to compare a new, continuous illumination and short Incubation time regimen of aminolevulinic acid photodynamic therapy#painless-PDT) to a conventional regimen for treatment o...

Eligibility Criteria

Inclusion

  • Clinical diagnosed with AK (OLSEN classification grade I, II, III), aged \> 18 years (Because no dosing or adverse event data are currently available on the use of topical aminolevulinic acid in patients \<18 years of age, children are excluded from this study);
  • All patients are unfit and reluctant to undergo surgery for any reasons, and volunteered to participate in the study and ability to understand and the willingness to sign a written informed consent. Patents are willing to pay for the treatment, and agreed to take a picture of the skin lesions.

Exclusion

  • Those who had ALA-PDT and any other studies that affect this study within 12 weeks ;
  • There are other facial diseases that may affect the efficacy evaluation, such as other photodermatosis;
  • Take phototoxic or photosensitizer within 8 weeks;
  • Clinical and / or pathological prove that the tumor has invaded other organs or tissues;
  • Serious immunocompromised persons;
  • scar constitution;
  • Patients are known to have skin photosensitivity, porphyria, or allergies to ALA, light or lidocaine;
  • Persons are suffering from severe internal diseases, mental and mental illness, infectious diseases or pregnant or lactating women.

Key Trial Info

Start Date :

May 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

April 30 2021

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT04396184

Start Date

May 1 2020

End Date

April 30 2021

Last Update

May 20 2020

Active Locations (1)

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1

Yunfeng Zhang

Shanghai, Jinan, China, 200443