Status:

WITHDRAWN

tVNS in Children With Prader-Willi Syndrome

Lead Sponsor:

Stanford University

Conditions:

Prader-Willi Syndrome

Social Behavior

Eligibility:

All Genders

8-14 years

Phase:

PHASE1

PHASE2

Brief Summary

The purpose of the current project is to test the impact of transcutaneous vagus nerve stimulation (tVNS) on social ability in children with Prader-Willi Syndrome (PWS). Social ability and blood neuro...

Eligibility Criteria

Inclusion

  • (1) be between the ages of 8-14 years; (2) have a confirmed diagnosis of PWS by genetic testing; (3) be minimally verbal and able to sit at a table to complete cognitive and behavioral testing; (4) be willing to provide blood samples; and (5) be willing to engage in a 16-week study period (baseline to intervention follow-up).

Exclusion

  • (1) currently taking oxytocin and/or arginine vasopressin or related analogs and (2) have a DSM-5 diagnosis of any severe mental or behavioral disorder (e.g. schizophrenia, bipolar disorder, conduct or oppositional defiant disorder) that significantly impacts daily functioning.

Key Trial Info

Start Date :

July 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

July 1 2021

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT04396470

Start Date

July 1 2020

End Date

July 1 2021

Last Update

May 6 2021

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