Status:
RECRUITING
CBD-Microglia PET Study
Lead Sponsor:
Yale University
Collaborating Sponsors:
National Center for Complementary and Integrative Health (NCCIH)
Conditions:
CBD
Healthy
Eligibility:
All Genders
18-55 years
Phase:
EARLY_PHASE1
Brief Summary
This study aims to examine the effect of cannabidiol (CBD) pre-treatment on brain microglial activation in healthy human subjects. Secondarily, this study aims to examine the effect of cannabidiol (CB...
Detailed Description
This study aims to examine the effect of cannabidiol (CBD), pre-treatment, as Epidiolex, on brain microglial activation in healthy human subjects using \[11C\]PBR28 PET imaging. Secondarily, this stud...
Eligibility Criteria
Inclusion
- Men and women aged 18- 55 years
- No significant medical or neurological illness
- No implanted metal devices that may pose a risk during MRI scanning
- Within the annual permissible radiation exposure
- Able to provide written informed consent.
Exclusion
- Current use of any medications
- Presence of metal in the body
- Pregnancy or lactation
Key Trial Info
Start Date :
May 7 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
September 30 2025
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT04398719
Start Date
May 7 2021
End Date
September 30 2025
Last Update
July 18 2025
Active Locations (1)
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1
Connecticut Mental Health Center
New Haven, Connecticut, United States, 06519