Status:

COMPLETED

Efficacy of a Modified Banxia Xiexin Decoction for the "Wei-Pi" Syndrome (Postprandial Distress Syndrome)

Lead Sponsor:

The University of Hong Kong

Collaborating Sponsors:

Hong Kong Buddhist Association

Conditions:

Postprandial Distress Syndrome

Eligibility:

All Genders

18-60 years

Phase:

NA

Brief Summary

The study aims to evaluate the efficacy of a modified Banxia Xiexin Decoction (BXD) for Wei-Pi through a randomized, waitlist controlled trial.

Detailed Description

After being informed about the study plan, potential risk and benefits, all subjects will give written informed consent prior to participation and undergo eligibility screening. Eligible participants ...

Eligibility Criteria

Inclusion

  • Permanent resident of Hong Kong with age from 18 to 60
  • Have a diagnosis of Wei-Pi (postprandial distress syndrome, ie. at least one of bothersome postprandial fullness (ie, severe enough to impact on usual activities) and bothersome early satiation (ie, severe enough to prevent finishing a regular-size meal) at least three days per week for the last three months, with symptom onset at least six months before diagnosis

Exclusion

  • Pregnancy or pregnancy planners
  • Abnormal liver function (up to twofold the upper normal reference level of ALT)\[14\] or kidney function (estimated creatinine clearance \< 80 mL/min)\[15\]
  • History of diagnosed gastric structural abnormalities through endoscopy /History of gastric removal surgery
  • Have G6PD deficiency
  • Alcohol or drug abuser
  • Taking Chinese medicine within one month
  • Unable to read/understand and sign the informed consent document

Key Trial Info

Start Date :

August 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 30 2021

Estimated Enrollment :

88 Patients enrolled

Trial Details

Trial ID

NCT04398888

Start Date

August 1 2020

End Date

September 30 2021

Last Update

July 29 2022

Active Locations (1)

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Hong Kong Buddhist Association - The University of Hong Kong Chinese Medicine Clinic cum Training and Research Centre (Wong Tai Sin District)

Hong Kong, Hong Kong