Status:
ENROLLING_BY_INVITATION
Additive Anti-inflammatory Action for Aortopathy & Arteriopathy
Lead Sponsor:
Nanjing Medical University
Collaborating Sponsors:
Beijing Anzhen Hospital
Conditions:
Acute Aortic Syndrome
Eligibility:
All Genders
18+ years
Brief Summary
Acute aortic syndrome (AAS) is a life-threatening condition. Inflammation plays a key role in the pathogenesis, development and progression of AAS, and is associated with significant mortality and mor...
Detailed Description
Aortopathy represent a major clinical challenge and are regarded as one of the leading causes of mortality among cardiovascular disorders. However, the pathological mechanisms underlying aortopathy ar...
Eligibility Criteria
Inclusion
- Inclusion criteria
- Aged 18 years or older.
- Patients with diagnosis of AAS, including aortic dissection, penetrating aortic ulcer or intramural hematoma.
- Symptoms started within 14 days from surgery.
- Patients received medical therapy, open surgical, endovascular, or hybrid repair.
- Any other major cardiac surgical procedure concomitant with surgery for AAS, such as coronary artery bypass grafting or carotid artery replacement;
- The patient or guardian agrees to participate in this study. Exclusion criteria
- Patients aged \< 18 years.
- Onset of symptoms \> 14 days from surgery.
- AAS secondary to traumatic or iatrogenic injury.
- Patients who declined participation in registration and follow-up investigation.
Exclusion
Key Trial Info
Start Date :
January 1 2016
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2040
Estimated Enrollment :
10000 Patients enrolled
Trial Details
Trial ID
NCT04398992
Start Date
January 1 2016
End Date
December 31 2040
Last Update
November 7 2024
Active Locations (29)
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1
Beijing Fuwai Hospital Chinese Academy of Medical Sciences
Beijing, Beijing Municipality, China
2
Chongqing Hospital of Jiangsu Provincial People's Hospital
Chongqing, Chongqing Municipality, China
3
Guangdong Provincial People's Hospital
Guangzhou, Guangdong, China
4
The First Affiliated Hospital of Guangxi Medical University
Nanning, Guangxi, China