Status:

RECRUITING

Apnea, Stroke and Incident Cardiovascular Events

Lead Sponsor:

University Hospital, Grenoble

Conditions:

Stroke

Sleep-disordered Breathing

Eligibility:

All Genders

18-85 years

Brief Summary

This prospective cohort study aims to compare the proportion of cardiac or cerebrovascular events after a first stroke, a first transient ischemic attack (TIA) or recurrent TIA, between sleep-disorder...

Detailed Description

This is a prospective cohort study that aims at comparing the proportion of incident cardiovascular events after a first stroke, first transient ischemic attack (TIA) or recurrent TIA, between sleep-d...

Eligibility Criteria

Inclusion

  • Male or female, aged 18 to 85 years
  • Admitted in the stroke unit no later than 72h after the onset of stroke symptoms:
  • First stroke confirmed by computed tomography scan or magnetic resonance imaging, whatever the localization
  • Initial or recurrent TIA, as defined by a brief and sudden neurological dysfunction for which an ischemic cause is presumed, with symptoms lasting less than 24 hours, and/or with no visible lesion on neuroimaging evaluation.
  • Score on the Modified Ranking scale (mRS) ≤1 before stroke
  • Signed informed consent by patient or his/her relative if not able
  • Patient eligible to carotid endarterectomy (for ancillary study only)

Exclusion

  • Pregnant or breastfeeding women
  • Past history of stroke
  • Inability to follow rehabilitation procedure
  • Patients with ongoing treatment for SDB
  • Exclusion period for another study
  • Patients not affiliated to a French social and health insurance system or equivalent
  • Prisoners or patients who require protection by the law

Key Trial Info

Start Date :

July 13 2020

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 1 2035

Estimated Enrollment :

1620 Patients enrolled

Trial Details

Trial ID

NCT04399200

Start Date

July 13 2020

End Date

June 1 2035

Last Update

February 11 2025

Active Locations (1)

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1

University Hospital Grenoble

Grenoble, France, 38043