Status:
ACTIVE_NOT_RECRUITING
Sentinel Lymph Node Mapping in Esophageal Cancer Using ICG Dye and NIR Imaging
Lead Sponsor:
Memorial Sloan Kettering Cancer Center
Conditions:
Esophageal Cancer
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of this study is to find out whether sentinel lymph node (SLN) mapping with ICG dye and NIR imaging can be used to identify esophageal or esophagogastric junction cancer that has spread to...
Eligibility Criteria
Inclusion
- Pathological diagnosis of adenocarcinoma tumor located in distal 1/3 of esophagus or esophagogastric junction , with a plan to undergo minimally invasive esophagectomy.
- All patients with Stage IVA (AJCC Cancer Staging Manual, 8th edition) disease will be eligible
- ≥18 years of age.
- Documented, signed, and dated informed consent, obtained before any procedures, for the proposed research study and for standard surgical resection.
Exclusion
- No plan to undergo surgical resection.
- Severe iodide or seafood allergy.
- Women of childbearing potential without a negative pregnancy test; or women who are lactating.
- Prior diagnosis of severe hepatic or renal dysfunction.
- Patients with Stage IVB or M1 disease (AJCC Cancer Staging Manual, 8th edition)
- Patients with local recurrence and planning to undergo salvage esophagectomy
Key Trial Info
Start Date :
May 20 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2026
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT04400292
Start Date
May 20 2020
End Date
May 1 2026
Last Update
July 3 2025
Active Locations (1)
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1
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
New York, New York, United States, 10065