Status:

COMPLETED

PROState Pathway Embedded Comparative Trial

Lead Sponsor:

Imperial College London

Collaborating Sponsors:

Imperial Clinical Trials Unit (ICTU)

Wellcome Trust

Conditions:

Prostate Cancer

Non-metastatic Prostate Cancer

Eligibility:

MALE

18+ years

Brief Summary

The proposal will explore a trial design called the cohort-multiple RCT (cmRCT) or as it has been recently coined, the Trials WithIn Cohorts (TWICS) design. This design has been used in a number of di...

Detailed Description

TRIAL AIMS The pilot phase of PROSPECT is interested in investigating the a) acceptability and feasibility of establishing the cohort of men, i.e. putting the questions of Point of Consent One to men...

Eligibility Criteria

Inclusion

  • Men aged 18 years old and over who are referred for investigations for urinary symptoms or elevated serum prostate specific antigen (PSA) levels or other risk factors for possible prostate malignancy.
  • An understanding of the English language sufficient to understand written and verbal information about the trial and consent process.
  • Estimated life expectancy of 5 years or more.
  • Signed informed consent.

Exclusion

  • 1\. Men who are unable to give informed consent.

Key Trial Info

Start Date :

September 8 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

August 31 2022

Estimated Enrollment :

139 Patients enrolled

Trial Details

Trial ID

NCT04400656

Start Date

September 8 2020

End Date

August 31 2022

Last Update

June 18 2025

Active Locations (3)

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Page 1 of 1 (3 locations)

1

West Middlesex University Hospital

Isleworth, Middlesex, United Kingdom, TW7 6AF

2

Ashford & St Peter's Hospitals (ASPH) NHS Foundation Trust

Chertsey, Surrey, United Kingdom, KT16 0PZ

3

Imperial College Healthcare NHS Trust

London, United Kingdom, W6 8RF