Status:
UNKNOWN
FFR and Inducible Myocardial Ischemia During Adenosine Stress Testing
Lead Sponsor:
Asan Medical Center
Conditions:
Coronary Artery Stenosis
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This is a prospective, single center study involving 150 patients with stable coronary artery disease undergoing coronary angiography for chest pain evaluation. The relationship between FFR values and...
Detailed Description
Fractional flow reserve (FFR) is commonly used to search for ischemia-producing lesions during percutaneous coronary intervention (PCI), and its assessment becomes an integral part to guide PCI when o...
Eligibility Criteria
Inclusion
- Men or women at least 18 years of age
- Patients undergoing coronary angiography
- Moderate to severe stenosis (diameter stenosis equal or more than 50 percent by visual examination) in one major epicardial coronary artery
- Normal left ventricular function without regional wall motion abnormality
Exclusion
- Contraindications to adenosine stress test\*
- ECG abnormalities (bundle branch block, LVH with strain, pacing rhythm, WPW)
- History of previous myocardial infarction
- Significant multi-vessel coronary artery disease (diameter stenosis equal or more than 50%)
- Hypertrophic cardiomyopathy
- Significant valvular heart disease
- Bronchial asthma or chronic obstructive lung disease
- Hepatic disease or biliary tract obstruction, or significant hepatic enzyme elevation (ALT or AST \> 3 times upper limit of normal).
- Current treatment for the active cancer
- Expected life expectancy \< 1 year
- Unwillingness or inability to comply with the procedures described in this protocol.
Key Trial Info
Start Date :
May 8 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
March 31 2022
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT04401657
Start Date
May 8 2020
End Date
March 31 2022
Last Update
July 21 2021
Active Locations (1)
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1
Asan Medical Center
Seoul, South Korea