Status:
RECRUITING
Rheumatology Patient Registry and Biorepository
Lead Sponsor:
Yale University
Collaborating Sponsors:
Rheumatology Research Foundation
Conditions:
Rheumatic Diseases
Adult Onset Still Disease
Eligibility:
All Genders
18-99 years
Brief Summary
To facilitate clinical, basic science, and translational research projects involving the study of rheumatic diseases.
Detailed Description
A rheumatology biorepository will be created to permit comparative analyses between the rheumatic diseases in order to increase the understanding of disease pathogenesis. Patients seen at Yale clinics...
Eligibility Criteria
Inclusion
- Inclusion Criteria for Rheumatology Patients:
- Patients ≥18 years old with a diagnosis of a rheumatic autoimmune disease including, but not limited to: adult onset Still's disease, ankylosing spondylitis, antiphospholipid syndrome, Behcet's disease, dermatomyositis, giant cell arteritis, mixed connective tissue disease, polymyalgia rheumatica, polymyositis, psoriatic arthritis, reactive arthritis, rheumatoid arthritis, sarcoidosis, scleroderma, Sjogren's syndrome, systemic lupus erythematosus, undifferentiated connective tissue disease and vasculitis.
- Receiving clinical care at Yale Rheumatology clinics
- Exclusion Criteria for Rheumatology Patients:
- Unable to provide informed consent
- No patients will be excluded based on gender or ethnicity or pregnancy status.
- Women who are currently pregnant will need to wait to donate a skin biopsy until after they deliver.
- Patients allergic to lidocaine or epinephrine or have a history of impaired wound healing will not be able to donate a skin biopsy.
- Inclusion Criteria for Healthy Volunteers:
- Age ≥ 18 years old
- No chronic skin conditions
- No diagnosis of a rheumatic autoimmune disease (e.g., lupus, rheumatoid arthritis)
- Normal BMI
- Exclusion Criteria for Healthy Volunteers:
- Unable to provide informed consent.
- Currently pregnant or nursing unless the study goal is to study pregnant or nursing woman.
- Allergies to lidocaine or epinephrine (skin biopsies).
- A history of impaired wound healing (skin biopsies).
Exclusion
Key Trial Info
Start Date :
August 4 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 1 2030
Estimated Enrollment :
5000 Patients enrolled
Trial Details
Trial ID
NCT04402086
Start Date
August 4 2020
End Date
June 1 2030
Last Update
March 6 2025
Active Locations (1)
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1
Yale New Haven Hospital
New Haven, Connecticut, United States, 06510