Status:
COMPLETED
The Role of Anti-inflammatory Cytokines and Antimicrobial Peptide LL-37 Biomarkers in the Treatment of Periodontal Disease.
Lead Sponsor:
Universidad Rey Juan Carlos
Conditions:
Periodontal Diseases
Periodontitis
Eligibility:
All Genders
18+ years
Brief Summary
Periodontal disease is an infectious pathology that consists of the destruction of the gums and supporting structures around the teeth. There are several mechanisms involved in this process. In health...
Detailed Description
'The role of anti-inflammatory cytokines and antimicrobial peptide LL-37 biomarkers in the treatment of periodontal disease. 1. Introduction Periodontal disease is an infectious process that cons...
Eligibility Criteria
Inclusion
- The criteria for entry were as follows: aged 18 or over, with no previous history of periodontal treatment in the last six months, and no medical or dental history that could contraindicate periodontal treatment. Exclusion criteria included current pregnancy or lactation, immunological disorders, periodontal treatment within the last 6 months, oral contraception and antibiotic usage within the last 3 months, infections (such as HIV, hepatitis, and tuberculosis). In addition, third molar teeth were excluded from GCF sampling for being often impacted or extracted
Exclusion
Key Trial Info
Start Date :
May 17 2021
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 15 2022
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT04404335
Start Date
May 17 2021
End Date
July 15 2022
Last Update
September 30 2022
Active Locations (1)
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1
Clinica Universitaria Universidad Rey Juan Carlos
Alcorcón, Madrid, Spain, 28923