Status:

COMPLETED

The Efficacy of N-acetylcysteine Versus Placebo for the Treatment of Metamphetamine Withdrawal Symptoms

Lead Sponsor:

Melva Louisa

Conditions:

Methamphetamine Dependence in Remission

Eligibility:

All Genders

18-60 years

Phase:

PHASE2

PHASE3

Brief Summary

Up to date, no approved medications are available for the treatment of methamphetamine addiction. Recently, N-acetylcysteine is recently being studied for methamphetamine withdrawal. N-acetylcysteine...

Detailed Description

Methamphetamine is a stimulant commonly abused worldwide. Methamphetamine can produce a rapid pleasurable rush caused by release of dopamine, nor-ephinephrine and serotonin. It produces euphoria, a he...

Eligibility Criteria

Inclusion

  • Men or women, 18 - 60 years old
  • Diagnosed with methamphetamine addiction based on DSM-V criteria, enrolling for methamphetamine withdrawal treatment
  • Agree to participate in the trial by signing informed consent

Exclusion

  • Known hypersensitivity to N-acetylcysteine
  • Patients with serious conditions that will not allow protocol compliance or safe participation in the clinical trials.
  • Pregnant or breastfeeding women
  • History of suicidal thoughts / behaviour
  • History of N-acetylcysteine treatment
  • History of asthma and convulsions

Key Trial Info

Start Date :

October 1 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 30 2020

Estimated Enrollment :

66 Patients enrolled

Trial Details

Trial ID

NCT04405193

Start Date

October 1 2019

End Date

December 30 2020

Last Update

February 10 2021

Active Locations (1)

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Rehabilitation Center, National Narcotics Agency

Bogor, West Java, Indonesia, 16110