Status:

UNKNOWN

Tight End-tidal Gas Control During Anesthesia to Decrease Postoperative Delirium Anesthetic Management

Lead Sponsor:

University of Manitoba

Conditions:

Post-Operative Confusion

Delirium

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

Respiratory end-tidal gas control is a fundamental of anesthetic management. The range of end-tidal (ET) O2 and CO2 during the conduct of anesthesia is far outside that found in the awake state. Recen...

Detailed Description

A. Background and Rationale: Although respiratory end-tidal gas control is a fundamental principle of anesthetic management, the range of end-tidal (ET) O2 and CO2 typically seen during the conduct o...

Eligibility Criteria

Inclusion

  • able to provide informed consent
  • elective major surgery requiring a minimum stay of 2 days postoperatively
  • no contraindication to MRI

Exclusion

  • unable to provide informed consent
  • CO2 retention with Chronic Obstructive Pulmonary Disease (COPD)
  • active congestive heart failure (CHF)
  • unable to participate adequately in delirium screening including those who are blind, deaf, illiterate or not fluent English or French
  • prior episode of intraoperative awareness

Key Trial Info

Start Date :

June 15 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 31 2021

Estimated Enrollment :

12 Patients enrolled

Trial Details

Trial ID

NCT04406350

Start Date

June 15 2020

End Date

December 31 2021

Last Update

May 28 2020

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Health Sciences Centre

Winnipeg, Manitoba, Canada, R3A 1R9

Tight End-tidal Gas Control During Anesthesia to Decrease Postoperative Delirium Anesthetic Management | DecenTrialz