Status:
COMPLETED
Oral and Systemic Levels of TFF-1 and TTF-3 in Periodontal Diseases
Lead Sponsor:
Aydin Adnan Menderes University
Conditions:
Periodontal Diseases
Eligibility:
All Genders
25-49 years
Brief Summary
Trefoil factor family (TFF) consists of a group of small peptides that have key roles in host immune response and repair of tissue damage. Interleukin (IL)-1β is a regulatory proinflammatory cytokine ...
Detailed Description
A total of one hundred participants were enrolled for the study. All individuals were assessed clinically and radiographically. Full-mouth clinical periodontal examinations were performed by the measu...
Eligibility Criteria
Inclusion
- Systemically healthy individuals
- No history of smoking
- Individuals between the ages of 25-50 years
- Having at least 20 natural teeth
Exclusion
- Any systemic disorders (i.e. diabetes mellitus, cardiovascular diseases, rheumatoid arthritis, immunological disorders, collagen-metabolic diseases, cancer)
- A history of smoking
- Pregnancy or lactation
- A history of surgical/non-surgical periodontal therapy in the past 1 year
- Drug therapy (e.g. anti-inflammatory, antibiotic treatment or any other pharmacological treatment) in the previous 6 months
Key Trial Info
Start Date :
July 1 2017
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 1 2018
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04407026
Start Date
July 1 2017
End Date
April 1 2018
Last Update
May 29 2020
Active Locations (1)
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1
Zeynep Pinar Keles Yucel
Giresun, Turkey (Türkiye)