Status:

COMPLETED

PErfusioN, OxyGen ConsUmptIon and ENergetics in ADPKD (PENGUIN)

Lead Sponsor:

University of Colorado, Denver

Conditions:

Polycystic Kidney Disease, Adult

Polycystic Kidney, Autosomal Dominant

Eligibility:

All Genders

18-40 years

Brief Summary

Autosomal dominant polycystic kidney disease (ADPKD) is the most common monogenic cause of end-stage kidney disease (ESKD). The disorder is characterized by development and continued growth of multipl...

Eligibility Criteria

Inclusion

  • Patients with Autosomal dominant polycystic kidney disease
  • Age 18-40 years
  • BMI \>= 18.5 and \<30 kg/m2
  • Weight \<350 lbs

Exclusion

  • Diabetes mellitus, based on previous diagnosis
  • Albuminuria (≥30mg/g) or estimated glomerular filtration rate (eGFR) \<75ml/min/1.73m2
  • Pregnancy or nursing
  • Anemia
  • Allergy to shellfish or iodine
  • Vaptan therapy (e.g. tolvaptan)
  • Uncontrolled hypertension (average ≥140/90 mmHg)

Key Trial Info

Start Date :

November 1 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

October 13 2022

Estimated Enrollment :

22 Patients enrolled

Trial Details

Trial ID

NCT04407481

Start Date

November 1 2020

End Date

October 13 2022

Last Update

February 3 2023

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Children's Hospital Colorado

Aurora, Colorado, United States, 80045