Status:
UNKNOWN
AKI Biomarkers in Coronavirus(COVID)-19
Lead Sponsor:
Guy's and St Thomas' NHS Foundation Trust
Collaborating Sponsors:
University Hospital Muenster
Conditions:
COVID
Acute Respiratory Failure
Eligibility:
All Genders
18+ years
Brief Summary
This research aims to investigate the role of daily measurement of urinary cell cycle arrest markers and other serum and urinary biomarkers to predict the development of acute kidney injury in critica...
Detailed Description
COVID-19 is a rapidly evolving pandemic with approximately 5% of all patients requiring admission to an intensive care unit. In critically ill patients with COVID-19, acute respiratory disease and acu...
Eligibility Criteria
Inclusion
- Moderate or severe respiratory disease as defined by Berlin criteria
- COVID-19 positive
- Age ≥ 18 years
Exclusion
- pre-existing AKI
- severe chronic kidney disease (CKD) with estimated glomerular filtration rate (eGFR) \<20ml/min
- end-stage renal failure on regular dialysis
- kidney transplant within the last 12 months
- pregnancy
- breastfeeding
Key Trial Info
Start Date :
August 20 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2022
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT04408248
Start Date
August 20 2020
End Date
December 31 2022
Last Update
March 15 2022
Active Locations (1)
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1
Guy's & St Thomas' Hospital
London, United Kingdom, SE1 7EH