Status:

COMPLETED

PRognOstiC valuE of rEd Density in Ulcerative Colitis

Lead Sponsor:

Universitaire Ziekenhuizen KU Leuven

Collaborating Sponsors:

Sapporo Medical University

Imelda GI Clinical Research Center

Conditions:

Ulcerative Colitis

Eligibility:

All Genders

16+ years

Brief Summary

Observational prospective multicenter study: baseline assessement of the disease activity by an automated endoscopic tool and follow up of 52 weeks to evaluate sustained clinical remission.

Eligibility Criteria

Inclusion

  • Confirmed diagnosis of UC for at least 3 months
  • Clinical remission with SCCAI \<3 at baseline and stable remission for the last 3 months
  • Ability to give informed consent by the patient or legal representative in case of minority.

Exclusion

  • Any contraindication for sigmoidoscopy or undergoing biopsies of the rectosigmoid.
  • Uncontrolled coagulopathy.
  • Any planned change in UC related treatment (both escalation and de-escalation) after the baseline endoscopy
  • Planned UC related surgery
  • Previous subtotal or total colectomy
  • Short bowel, ileostomy or colostomy
  • Pregnancy at baseline
  • Age younger than 16 years

Key Trial Info

Start Date :

August 3 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 1 2022

Estimated Enrollment :

243 Patients enrolled

Trial Details

Trial ID

NCT04408703

Start Date

August 3 2020

End Date

June 1 2022

Last Update

June 27 2024

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Imelda GI clinical research center

Bonheiden, Belgium, 2820

2

UZ Leuven

Leuven, Belgium, 3000