Status:

COMPLETED

Stress Induced by Screening for Retinopathy of Prematurity - Should Speculum and Indentation Rather be Avoided

Lead Sponsor:

Aristotle University Of Thessaloniki

Conditions:

Retinopathy of Prematurity

Eligibility:

All Genders

30-37 years

Phase:

NA

Brief Summary

The purpose is to assess the hypothesis that indirect ophthalmoscopy for retinopathy of prematurity eye examination (ROPEE) screening without the use of a lid speculum and scleral indentation (speculu...

Detailed Description

A prospective randomized cross-over study was conducted for the comparison of the two techniques of funduscopy for ROPEE screening, i.e. with (Sp) or without (SpF) the use of a speculum and indentor. ...

Eligibility Criteria

Inclusion

  • Preterm neonates undergoing screening for ROP, i.e.
  • with GA \< 32weeks and/or BW \< 1501grams
  • infants of greater BW and GA with increased comorbidity, e.g. sepsis, prolonged need for oxygen supplementation etc., as judged by the attending neonatologist

Exclusion

  • Severe clinical condition with unstable vital signs to the extent that stress is not desired and the examination need to be postponed.
  • Diagnosis of traumatic apoptosis of the corneal epithelium / corneal ulcer.
  • Neonates under sedative/analgesic treatment.
  • Intraventricular hemorrhage (III,IV degree), moderate/severe neurological impairment, other conditions that could alter pain response.

Key Trial Info

Start Date :

September 3 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 27 2020

Estimated Enrollment :

37 Patients enrolled

Trial Details

Trial ID

NCT04408807

Start Date

September 3 2019

End Date

February 27 2020

Last Update

March 24 2022

Active Locations (1)

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1

"Papageorgiou" Hospital

Thessaloniki, Greece