Status:

UNKNOWN

Viscoelasticity Imaging to Assess Liver Cancer

Lead Sponsor:

Centre hospitalier de l'Université de Montréal (CHUM)

Collaborating Sponsors:

Siemens Corporation, Corporate Technology

Fonds de la Recherche en Santé du Québec

Conditions:

Liver Cancer

Eligibility:

All Genders

18+ years

Brief Summary

Ultrasound (US) used for hepatocellular carcinoma (HCC) surveillance suffers from low sensitivity (60-78%) due to fatty liver, obesity, and diffusely nodular appearance in cirrhosis. Once a suspicious...

Detailed Description

RESEARCH QUESTION AND BACKGROUND: Primary liver cancer or hepatocellular carcinoma (HCC) is the fifth most common cancer in men and the seventh in women and is the second cause of cancer mortality wor...

Eligibility Criteria

Inclusion

  • Are at least 18 years old at screening;
  • Able to comprehend and willingness to provide voluntary consent;
  • Are able to have a MRI;
  • Understand French or English;
  • Patients enrolled in a monitoring program or referred for the characterization of a focal liver lesion;
  • Focal liver lesion is visible during ultrasound screening in B-mode.

Exclusion

  • Are pregnant or trying to become pregnant;
  • Have a weight or girth preventing from entering the MR magnet bore;
  • Are unable to understand or unwilling to provide written informed consent for this study;
  • Have a contraindication to MRI (pacemaker, insurmountable claustrophobia);
  • Have chronic kidney disease preventing the injection of gadolinium-based contrast agent.

Key Trial Info

Start Date :

October 5 2020

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 22 2023

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT04409340

Start Date

October 5 2020

End Date

December 22 2023

Last Update

October 2 2023

Active Locations (1)

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Centre hospitalier de l'Université de Montréal (CHUM)

Montreal, Quebec, Canada, H2X 0A9