Status:

COMPLETED

Domiciliary Versus Hospital Management of PPROM

Lead Sponsor:

Ahmed Mohammed Selim

Conditions:

Preterm Premature Rupture of Membrane

Eligibility:

FEMALE

Brief Summary

This study is designed to compare efficacy \& safety of planned domiciliary versus hospital care for women with preterm prelabor rupture of the membranes (PPROM) on fetal, neonatal and maternal outcom...

Detailed Description

Background: PPROM is encountered in 2.0% to 3.5% of pregnancies. Domiciliary care management is developing more and more in obstetrics, with psychological benefits for patients as well as other financ...

Eligibility Criteria

Inclusion

  • Inclusion Criteria include women with PPROM ≥28 weeks \& \<37 weeks with no signs of intra-amniotic infection \& membranes rupture is confirmed by a sterile speculum examination and decrease amniotic fluid on ultrasound with singleton, viable, cephalic presenting fetus, morphologically normal fetus by ultrasound \& reactive fetal heart rate tracing with no evidence of meconium-stained liquor
  • Exclusion Criteria:
  • Query PPROM: A history of PPROM with no pooling of amniotic fluid from the cervix on a sterile speculum examination
  • Maternal comorbidities (Diabetes mellitus, hypertension, etc.)
  • Patients with placenta previa
  • Amniotic fluid pocket on ultrasound \< 2x2 cm
  • Logistic problems interfering with follow-up
  • Inability to check temperature every six hours, with parameters for notifying their clinician (temperature ≥38°C)
  • Non-Dependable transportation

Exclusion

    Key Trial Info

    Start Date :

    April 15 2019

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    October 20 2020

    Estimated Enrollment :

    3662 Patients enrolled

    Trial Details

    Trial ID

    NCT04413019

    Start Date

    April 15 2019

    End Date

    October 20 2020

    Last Update

    January 6 2021

    Active Locations (1)

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    Faculty of medicine - Ain Shams university

    Cairo, Egypt, 11517