Status:

ACTIVE_NOT_RECRUITING

Delayed Cord Clamping With Oxygen In Extremely Low Gestation Infants

Lead Sponsor:

Sharp HealthCare

Collaborating Sponsors:

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

Sharp Mary Birch Hospital for Women & Newborns

Conditions:

IVH- Intraventricular Hemorrhage

Extreme Prematurity

Eligibility:

All Genders

22-28 years

Phase:

NA

Brief Summary

This study is being conducted to compare the incidence of preterm infants (up to 28+6 weeks GA) who achieve a peripheral oxygen saturation of 80 percent by 5 minutes of life (MOL) given mask CPAP/PPV ...

Detailed Description

Prenatal consent will be obtained on infant's with estimated gestational age up to 28+6 weeks. Shortly before delivery, infant's will be randomly assigned to receive either Low oxygen concentration (F...

Eligibility Criteria

Inclusion

  • up to 28+6 weeks Gestational age
  • Single and Multiple pregnancy
  • All modes of delivery (vaginally or caesarean section)

Exclusion

  • Parents decline consent
  • Congenital anomalies of the newborn
  • Bleeding Accreta
  • Monochorionic multiples with evidence of TTTS
  • Fetal or maternal risk (i.e. compromise)
  • Preterm Premature Rupture of Membranes prior to 20 weeks gestation
  • Parents request no resuscitation

Key Trial Info

Start Date :

November 17 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 31 2026

Estimated Enrollment :

140 Patients enrolled

Trial Details

Trial ID

NCT04413097

Start Date

November 17 2021

End Date

May 31 2026

Last Update

June 12 2025

Active Locations (3)

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Page 1 of 1 (3 locations)

1

University of California Davis

Davis, California, United States, 95817

2

University of California San Diego Jacobs Medical Center

San Diego, California, United States, 92037

3

Sharp Mary Birch Hospital for Women and Newborns

San Diego, California, United States, 92123