Status:

COMPLETED

Effect of IATP on Cognitive Functioning in Anxious Older Adults.

Lead Sponsor:

The Hong Kong Polytechnic University

Conditions:

Anxiety Symptoms

Eligibility:

All Genders

60-90 years

Phase:

NA

Brief Summary

Older adults with anxiety symptoms was found to be associated with greater risk of dementia. Interventions targeting signs as early as in the pre-symptomatic phase could be most effective in early pre...

Detailed Description

Older adults with anxiety disorders or symptoms are not in the consideration of management for dementia prevention. However, the condition is found to be associated with profound negative subsequent d...

Eligibility Criteria

Inclusion

  • Older adults aged 60 - 90 years; and
  • Presence of subjective memory complaints as measured by memory inventory for the Chinese; and
  • Anxiety symptoms as measured by Hamilton Anxiety Scale (HAM-A) with a score of 18 or above (indicated as mild anxiety symptoms).

Exclusion

  • DSM-5 diagnosis of either Major Neurocognitive Disorder due to AD, or Major Vascular Neurocognitive Disorder with small vessel disease. This would include satisfying criteria for significant cognitive decline in at least one of six areas of cognition (memory, perceptual-motor, complex attention, language, executive function and social cognition), and with clinical or neuroimaging features indicative of either AD or small vessel disease; or;
  • Clinical dementia rating larger than or equal to 0.5; or
  • Clinically depressed as assessed by Hamilton Depression Rating Scale with a score of 20 or higher; or
  • Past history of major depressive episode, bipolar affective disorders or psychosis; or
  • Physical frailty that may affect attendance to training sessions; or
  • Currently on psychotropic or other medications know to affect cognition (e.g., benzodiazepines, anti-dementia medication, etc.); or
  • Participants in other cognitive training or intervention for brain health during the study period; or
  • Presence of major neurological deficit including history of stroke, transient ischemic attack or traumatic brain injury; or
  • Significant communicative impairment.

Key Trial Info

Start Date :

August 13 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 7 2019

Estimated Enrollment :

48 Patients enrolled

Trial Details

Trial ID

NCT04413513

Start Date

August 13 2018

End Date

January 7 2019

Last Update

June 4 2020

Active Locations (1)

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The Hong Kong Polytechnic University

Hong Kong, Hong Kong