Status:

UNKNOWN

Impact of Photopheresis in the Prevention of Acute Rejection in Highly Sensitized de Novo Kidney Transplant Recipients

Lead Sponsor:

Fundacion Clinic per a la Recerca Biomédica

Collaborating Sponsors:

Mallinckrodt

Conditions:

Kidney Transplant Rejection

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

The aim of the present study is to evaluate the superiority of photopheresis in combination with the standard immunosuppression vs standard immunosuppression alone for the prevention of acute rejectio...

Eligibility Criteria

Inclusion

  • Sensitized (cPRA ≥90%) candidates for a deceased-donor kidney transplantation
  • Recipients between 18 and 75 years old
  • Patients are able to understand and sign informed consent (Annex 1).

Exclusion

  • Participation in another interventional clinical trial.
  • Use of Rituximab or Eculizumab at the time of transplant or in the first 24 hours post-transplant.
  • Persons with any dependency on the researcher or employee by the responsible institution or researcher. As well as people detained by legal order.

Key Trial Info

Start Date :

August 17 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2025

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT04414735

Start Date

August 17 2022

End Date

December 1 2025

Last Update

July 6 2023

Active Locations (1)

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1

Deparment of Nephology and Kidney Transplant

Barcelona, Please Select, Spain, 08036