Status:

COMPLETED

Pharmacologic Augmentation of Targeted Cognitive Training in Schizophrenia

Lead Sponsor:

University of California, San Diego

Conditions:

Schizophrenia

Schizoaffective Disorder

Eligibility:

All Genders

18-55 years

Phase:

PHASE2

Brief Summary

These studies look to conduct efficient pilot testing of a novel intervention strategy for chronic psychotic disorders - Pharmacologic Augmentation of Cognitive Therapy (PACT) - via an experimental me...

Detailed Description

Subjects who meet criteria for study entry come to UCSD where consenting and a comprehensive screening and diagnostic assessment including a Mini-International Neuropsychiatric Interview are conducted...

Eligibility Criteria

Inclusion

  • Inclusion criteria include:
  • DSM-IV diagnosis of schizophrenia or schizoaffective disorder, depressed type
  • Written informed consent to participate in the study
  • Age 18 - 55
  • Absence of dementia or mental retardation
  • Urine toxicology negative for recreational drugs
  • Fluent and literate in English (needed for completion of WIN and QuickSIN)
  • Exclusion criteria include:
  • Meets DSM-IV criteria for current substance abuse or dependence and has been substance abstinent for less than 30 days
  • A history of traumatic brain injury
  • Auditory or visual impairments severe enough to prevent study participation
  • Under conservatorship (determined by Anasazi)
  • Pregnancy

Exclusion

    Key Trial Info

    Start Date :

    November 9 2020

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    December 30 2024

    Estimated Enrollment :

    68 Patients enrolled

    Trial Details

    Trial ID

    NCT04414930

    Start Date

    November 9 2020

    End Date

    December 30 2024

    Last Update

    December 17 2025

    Active Locations (1)

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    Clinical Teaching Facility (CTF-B102) at UCSD Medical Center

    San Diego, California, United States, 92103