Status:

TERMINATED

Esophageal Multisegmented FCSEMS for Malignant Strictures

Lead Sponsor:

Radboud University Medical Center

Collaborating Sponsors:

Erasmus Medical Center

Conditions:

Oesophageal Cancer

Esophageal Stent Stenosis

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Objective: To assess the safety and feasibility of the implementation of the esophageal multisegmented fully covered self-expandable metal stent (SEMS) for the palliation of patients with malignant dy...

Eligibility Criteria

Inclusion

  • Inclusion criteria:
  • Patients presenting with dysphagia due to a non-operable malignant obstruction of the esophagus or esophagogastric junction including extrinsic malignant compression and recurrence in post-esophagectomy patients;
  • Requiring treatment for dysphagia (Ogilvie score of 2-41);
  • Life expectancy of less than 12 months.
  • Exclusion criteria:
  • Stenosis after laryngectomy;
  • Distance between the upper edge of the stent less than 2 cm from the upper esophageal sphincter;
  • Esophageal fistula;
  • Tumor length of more than 14 cm;
  • Previous stent placement for the same condition;
  • Inappropriate cultural level and understanding of the study;
  • Coagulopathy;
  • Patients with eosinophilic esophagitis or an esophageal motility disorder;
  • Nickel titanium (Nitinol) allergy.

Exclusion

    Key Trial Info

    Start Date :

    March 3 2021

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    December 1 2022

    Estimated Enrollment :

    23 Patients enrolled

    Trial Details

    Trial ID

    NCT04415463

    Start Date

    March 3 2021

    End Date

    December 1 2022

    Last Update

    January 12 2023

    Active Locations (1)

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    Page 1 of 1 (1 locations)

    1

    Radboudumc

    Nijmegen, Gelderland, Netherlands, 6500