Status:
COMPLETED
Inspiratory Muscle Training and COPD
Lead Sponsor:
Brno University Hospital
Conditions:
Chronic Obstructive Pulmonary Disease
Eligibility:
All Genders
40+ years
Phase:
NA
Brief Summary
Subjects with chronic obstructive pulmonary disease (COPD) frequently develop considerable deterioration in exercise capacity in association with weakness and deconditioning of the respiratory muscles...
Detailed Description
Eligible participants will be randomly assigned to one of the following three distinct home-based IMT protocols: (1) TIRE, (2) Standard, and (3) Sham (i.e. Low Resistance). All subjects will undergo 8...
Eligibility Criteria
Inclusion
- individuals over the age of 40
- clinical and functional diagnosis of COPD
- Global Initiative of Chronic Obstructive Lung Disease (GOLD) - stages I to IV
- evidence of inspiratory muscle weakness, defined as a MIP ≤ 80 cmH2O and a SMIP ≤ 427 PTU
- ability to operate a computer, tablet or smartphone
- clinical stability with no history of infections or exacerbation of respiratory symptoms for at least two months prior to study enrollment
- non-participation in exercise programs in the past 12 months.
Exclusion
- subjects with history of lung surgery, lung cancer,
- any diagnosed cognitive (i.e. Mini Mental State Examination score \< 24),
- orthopedic, neurological or neuromuscular disorders
Key Trial Info
Start Date :
May 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2024
Estimated Enrollment :
48 Patients enrolled
Trial Details
Trial ID
NCT04415788
Start Date
May 1 2021
End Date
December 31 2024
Last Update
February 5 2025
Active Locations (1)
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1
University Hospital Brno
Brno, Czechia, 62500