Status:

ENROLLING_BY_INVITATION

B3 for NMD: Bench to Bedside and Back

Lead Sponsor:

Ottawa Hospital Research Institute

Conditions:

Neuromuscular Disease

Eligibility:

All Genders

18+ years

Brief Summary

Background: Neuromuscular diseases (NMD) represent a broad group of rare genetic and acquired disorders, affecting over 300,000 people in Canada. Given the multiple different NMD subtypes, almost half...

Detailed Description

The B3 for NMD creates a streamlined approach to develop the Bench (preclinical and laboratory characterization) to Bedside (clinical and imaging assessment) and Back (biomarker, diagnostics and thera...

Eligibility Criteria

Inclusion

  • Patients or blood relatives of patients classified as having a neuromuscular disease from the following categories:
  • Motor Neuron Disease (Amyotrophic Lateral Sclerosis/Spinal Muscular Atrophy)
  • Neuropathies
  • Neuromuscular Junction Disorders
  • Myopathies.

Exclusion

  • Patients referred to the neurology clinic without a neuromuscular disorder:
  • Central nervous system disorders such as Stroke
  • Multiple Sclerosis
  • Parkinson's disease

Key Trial Info

Start Date :

May 6 2019

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 31 2033

Estimated Enrollment :

500 Patients enrolled

Trial Details

Trial ID

NCT04417023

Start Date

May 6 2019

End Date

December 31 2033

Last Update

December 30 2025

Active Locations (1)

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1

Ottawa Hospital Research Institute

Ottawa, Ontario, Canada, K1Y4E9