Status:
COMPLETED
Serum A.Actinomycetemcomitans Antibodies and Periodontitis
Lead Sponsor:
University of Messina
Conditions:
Periodontal Diseases
Eligibility:
All Genders
34-72 years
Brief Summary
The aim of this study was to analyze the association between serum A.actinomycetemcomitans antibodies in patients with periodontitis. Furthermore, the objective was to determine if the periodontitis i...
Detailed Description
53 patients with periodontitis and 48 healthy subjects (HS) were enrolled in the present study. Enrolled patients were examined and characterized for clinical and blood samples analysis and A.actinomy...
Eligibility Criteria
Inclusion
- Presence of at least 15 teeth
- CP with a minimum of 40% of sites with a clinical attachment level (CAL)
- ≥2mm and probing depth (PD) ≥4mm;
- Presence of at least ≥2 mm of crestal alveolar bone loss verified on digital periapical radiographs
- Presence of ≥40% sites with bleeding on probing (BOP)
Exclusion
- Intake of contraceptives
- Intake of immunosuppressive or anti-inflammatory drugs throughout the last three months prior to the study
- Status of pregnancy or lactation
- Previous history of excessive drinking
- Allergy to local anaesthetic
- Intake of drugs that may potentially determine gingival hyperplasia such as Hydantoin, Nifedipine, Cyclosporin A or similar drugs.
Key Trial Info
Start Date :
April 15 2016
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 25 2020
Estimated Enrollment :
221 Patients enrolled
Trial Details
Trial ID
NCT04417322
Start Date
April 15 2016
End Date
March 25 2020
Last Update
June 4 2020
Active Locations (1)
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1
University of Messina
Messina, Italy, 98100