Status:

COMPLETED

Opsin Receptors in Melasma

Lead Sponsor:

Universidad Autonoma de San Luis Potosí

Collaborating Sponsors:

Hospital Central "Dr. Ignacio Morones Prieto"

Conditions:

Melasma

Eligibility:

FEMALE

18-60 years

Phase:

NA

Brief Summary

Melasma is a hyperpigmentation disorder that is probably exacerbated by visible light. Opsin receptors (OPN 1, 2, 3, 4 y 5) were described in the skin, being capable of activating melanogenesis induce...

Eligibility Criteria

Inclusion

  • Patients diagnosed with melasma, of 18 years of age and older, without previous treatment or photoprotection measures within the previous 4 weeks, who had Melasma Activity and Severity Index (MASI) scores higher than 7

Exclusion

  • pregnancy or nursing, menopause, coexistence of other pigmentation conditions, heat exposure, regular exercise, diet restriction, consumption of food supplements or any type of drugs (including anti-inflammatories and hormonal treatments) within the previous 2 months, and women who had given birth within 1 year

Key Trial Info

Start Date :

January 31 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 15 2019

Estimated Enrollment :

15 Patients enrolled

Trial Details

Trial ID

NCT04417348

Start Date

January 31 2019

End Date

December 15 2019

Last Update

June 4 2020

Active Locations (1)

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1

Dermatology Department. Hospital Central "Dr. Ignacio Morones Prieto"

San Luis Potosí City, Mexico, 78290