Status:

COMPLETED

Improving PET Image Quality and Quantification by Using Motion Correction, Parametric Imaging and MAP Reconstruction

Lead Sponsor:

Mayo Clinic

Conditions:

Brain Imaging

Whole Body Imaging

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

The purpose of this study is to assess the effectiveness of new software available on a new PET/CT scanner in the Molecular Imaging Research PET/CT Facility. Further, the study aims to evaluate the da...

Detailed Description

The study will be separated into three cohorts: Motion Correction, Parametric Imaging, and MAP Reconstruction. The motion correction (Aim 1) cohort will involve a group of 30 subjects who are already ...

Eligibility Criteria

Inclusion

  • 18 years of age or older
  • Subjects who are able and willing to sign the informed consent
  • Subjects who are able to follow verbal commands
  • A negative urine pregnancy test within 48 hours prior to PET imaging procedures in females of childbearing potential
  • Subjects who are scheduled for a PET/CT study under Mayo Clinic Rochester IRB research protocol 08-005553 (Aim 1 cohort only)
  • A positive 18F-FDG oncology PET/CT exam in the last six months (Aim 2 cohort only)

Exclusion

  • Patients who are unable to lay still for an additional 15 minutes (for Aim 1 cohort)
  • Patients who are unable to lay still for 90 min for 18F-FDG scans or 100 min for 18F-AV1451 scans (for Aim 2 cohort)
  • Patients who cannot follow the prep instructions

Key Trial Info

Start Date :

June 3 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 20 2023

Estimated Enrollment :

80 Patients enrolled

Trial Details

Trial ID

NCT04417998

Start Date

June 3 2020

End Date

December 20 2023

Last Update

January 22 2025

Active Locations (1)

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Mayo Clinic in Rochester

Rochester, Minnesota, United States, 55905