Status:

COMPLETED

Efficacy of SLN Block for Chronic Cough

Lead Sponsor:

Medical University of South Carolina

Conditions:

Cough

Superior Laryngeal Nerve Block

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

This is a research study to find out if superior laryngeal nerve blocks are an effective way to reduce cough when compared to placebo (a substance without any medical value). Eligibility for the study...

Eligibility Criteria

Inclusion

  • History consistent with neurogenic cough
  • Exclusion of other etiologies (see exclusion criteria)
  • Age ≥ 18

Exclusion

  • Current neuromodulating medication use
  • Untreated other etiologies of cough:
  • Current smoker Current ACE/ARB use Abnormal PFTs within 6 months Uncontrolled OSA Abnormal CXR within 6 months RSI \> 13 or RFS \>11 AND workup positive for GERD (esophagram, 24-hour pH probe, manometry, EGD)

Key Trial Info

Start Date :

July 22 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 30 2022

Estimated Enrollment :

17 Patients enrolled

Trial Details

Trial ID

NCT04421092

Start Date

July 22 2020

End Date

December 30 2022

Last Update

October 23 2025

Active Locations (1)

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1

Medical University of South Carolina

Charleston, South Carolina, United States, 29403