Status:
COMPLETED
Investigation of the Serum Mucoprotein 3 (MUC3) Protein Levels in Gestational Hypertensive Disease
Lead Sponsor:
Karadeniz Technical University
Conditions:
Muc3
Pregnancy Induced Hypertension
Eligibility:
FEMALE
18-45 years
Brief Summary
Hypertensive diseases of pregnancy are one of the most frequently encountered reasons for maternal and neonatal morbidity and mortality. The excretion of high levels of mucoprotein takes part in the p...
Detailed Description
Hypertensive diseases of pregnancy are one of the most frequently encountered reasons for maternal and neonatal morbidity and mortality. The excretion of high levels of mucoprotein takes part in the p...
Eligibility Criteria
Inclusion
- To accept the consent to participate in the research and sign the form,
- According to ACOG 2002, pregnancy meets the criteria of hypertensive diseases \[1\], The diagnosis of HELLP syndrome was made according to the criteria described by Sibai. These; abnormal peripheral smear, schistocyte in the peripheral smear, lactate dehydrogenase \> 600 U / L, hemolysis, total bilirubin\> 1.2 mg / dl, AST\> 70 U / L, platelet count \<100,000mm3.
- When the demographic characteristics and CVs of all cases were questioned in the initial evaluation, not having chronic inflammation or acute infection, not having any systemic disease, recurrent pregnancy loss, thrombophilia, antiphospholipid antibody syndrome,
- Not smoking, No history of cancer, No multiple pregnancies
- Not using antihypertensive, anticoagulant, NSAID, corticosteroid or antiplatelet and antiepileptic drugs
Exclusion
- using antihypertensive, anticoagulant, NSAID, corticosteroid or antiplatelet and antiepileptic drugs
- smoking,history of cancer, multiple pregnancies
Key Trial Info
Start Date :
June 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 2 2011
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT04421183
Start Date
June 1 2010
End Date
January 2 2011
Last Update
June 9 2020
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Karadeniz Technique University
Trabzon, Ortahisar, Turkey (Türkiye), 61080