Status:
RECRUITING
Multimodal Investigation of Intracranial Clot Environment
Lead Sponsor:
University Hospital, Montpellier
Collaborating Sponsors:
Genomic Institute of Montpellier
Conditions:
Acute Ichemic Stroke
Brain Ischemia
Eligibility:
All Genders
18-100 years
Brief Summary
Analysis of peri clot blood collected at the acute phase of stroke in order to understand physiopathological mechanisms involved in the cerebrovascular damage
Detailed Description
It has been shown that immune cells accumulate around the clot at the acute phase of stroke. Leukocytes and their specific chemokines and cytokines regulation may impact cerebrovascular integrity.
Eligibility Criteria
Inclusion
- Inclusion criteria:
- Over 18 years of age,
- Non-dependent for activities of daily living prior to the onset of the MI (Modified Rankin Score \>2)
- Having an occlusion of a large arterial trunk proven by imaging (angio-MRI or angio-scanner).
- Exclusion criteria:
- Patients initially admitted but for whom endovascular treatment will not finally be performed (re-infusion, catheterization failure...) will be excluded from the study.
- Major patients under guardianship or curatorship or patients deprived of liberty
Exclusion
Key Trial Info
Start Date :
March 14 2021
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 1 2025
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT04421326
Start Date
March 14 2021
End Date
October 1 2025
Last Update
May 29 2024
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University Hospital of Montpellier
Montpellier, France