Status:
RECRUITING
Functional Changes in the Stomach and Esophagus After One Anastomosis Gastric Bypass- OAGB
Lead Sponsor:
Spital Limmattal Schlieren
Conditions:
Obesity, Morbid
GERD
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
Evaluation of the functional changes in the stomach and esophagus of patients undergoing One Anastomosis Gastric Bypass (OAGB)
Eligibility Criteria
Inclusion
- BMI\> 35 kg/m2
- 2 years of controlled conservative obesity treatment without weight reduction
- patients should give their consent to participate in the study
Exclusion
- Less than 2 years of conservative obesity treatment
- cancer
- cirrhosis Child-Pough score A
- Crohn's disease
- serious psychiatric disorder, which led to in-hospital treatment in psychiatric clinic in the past two years
- drug consumption
- non-compliance
- hiatal hernia \> 4cm
- gastric pouch \< 10cm
- Barett esophagus
- erosive esophagitis Grade C or D according to the Los Angeles Classification
- endoscopically proven gastric stricture
- acid exposition time \> 6% (Lyon criteria)
- reflux episodes\> 80 /24 hours (Lyon criteria)
- insufficient low esophageal sphincter according to manometry findings
- pathological findings in the impedance pH-metry (acid and non-acid reflux)
Key Trial Info
Start Date :
June 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 28 2035
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT04422405
Start Date
June 1 2020
End Date
May 28 2035
Last Update
June 6 2025
Active Locations (1)
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1
Limmattal Hospital
Schlieren, Canton of Zurich, Switzerland, 8952