Status:

COMPLETED

Foci of Tumor Heterogeneity in Diffuse Low-Grade Gliomas

Lead Sponsor:

University Hospital, Montpellier

Conditions:

Glioma

Eligibility:

FEMALE

18-70 years

Brief Summary

Background: Diffuse low-grade gliomas (DLGG) are slow-growing primary-cancer of the brain and spinal cord. They represent up to 15% of the developing tumors in those organs with fatal outcome for the...

Detailed Description

IDH1-mutated gliomas are slow-growing brain tumors which progress into high-grade gliomas. The early molecular events causing this progression are ill-defined. Previous studies revealed that 20% of th...

Eligibility Criteria

Inclusion

  • Inclusion criteria:
  • An individual must fulfill all of the following criteria in order to be eligible for study enrollment:
  • Aged between 18 and 70 years.
  • Suffering from IDH1-mutated diffuse low-grade glioma.
  • No pre operative nor oncology treatment prior to join the study.
  • Signed informed consent form.
  • Exclusion criteria:
  • Subject unable to read or/and write
  • Grade 3 or 4 gliomas
  • Tumor with IDH1-WT status

Exclusion

    Key Trial Info

    Start Date :

    November 1 2016

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    March 30 2019

    Estimated Enrollment :

    8 Patients enrolled

    Trial Details

    Trial ID

    NCT04423094

    Start Date

    November 1 2016

    End Date

    March 30 2019

    Last Update

    June 9 2020

    Active Locations (1)

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    Uh Montpellier

    Montpellier, France, 34295