Status:

COMPLETED

Effect of Non-psychoactive Cannabidiol as an Adjunct to Botulinum Toxin in Blepharospasm

Lead Sponsor:

Silkiss Eye Surgery

Collaborating Sponsors:

Benign Essential Blepharospasm Research Foundation

GW Pharmaceuticals Ltd

Conditions:

Blepharospasm

Blepharospasm, Benign Essential

Eligibility:

All Genders

18+ years

Phase:

PHASE2

PHASE3

Brief Summary

The planned study is a prospective analysis of non-psychoactive Cannabidiol (without THC) as an adjunctive therapy for blepharospasm in a masked double cross-over study. This prospective study is a fo...

Eligibility Criteria

Inclusion

  • Patients in the private practice of the principal investigator with an ICD code of "blepharospasm" and:
  • undergoing routine maximal botulinum therapy
  • experiencing break through symptoms of spasm
  • marijuana naïve

Exclusion

  • concomitant diagnosis of epilepsy
  • patients whom are not marijuana naive
  • patients on concurrent anti-epileptics
  • patients who are pregnant or wishing to become pregnant
  • patients not wishing to participate in the study.

Key Trial Info

Start Date :

May 20 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 1 2021

Estimated Enrollment :

12 Patients enrolled

Trial Details

Trial ID

NCT04423341

Start Date

May 20 2020

End Date

October 1 2021

Last Update

November 2 2021

Active Locations (1)

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Silkiss Eye Surgery

Oakland, California, United States, 94609