Status:
COMPLETED
Effects of Platelet Rich Plasma on Endometrium
Lead Sponsor:
Acibadem University
Collaborating Sponsors:
Baskent University
Conditions:
Asherman Syndrome
Eligibility:
FEMALE
20-45 years
Phase:
NA
Brief Summary
Intrauterine platelet rich plasma will be injected in the endometrial region via the vaginal route after the cessation of menstrual period. The endometrial thickness will be assessed under ultrasound ...
Detailed Description
Intrauterine platelet rich plasma will be injected in the endometrial region via the vaginal route after the cessation of menstrual period. In the second menstrual period following the PRP injection, ...
Eligibility Criteria
Inclusion
- Women in whom cycle was cancelled due to an endometrial thickness \<7 mm when progesterone start was planned in patients undergoing frozen embryo transfer with hormone replacement therapy
- Women with a history of Asherman syndrome, but no obvious intrauterine adhesion in the last hysteroscopic procedure;
- Women who have at least 2 frozen good-quality embryos.
Exclusion
- Women with any other known cause of implantation failure, such as poor embryo quality, or congenital uterine anomalies, endometrial polyp or fibroid,
- Previous diagnosis of any malignancy,
- Anticoagulant use for which plasma infusion is contraindicated,
Key Trial Info
Start Date :
September 15 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 19 2021
Estimated Enrollment :
150 Patients enrolled
Trial Details
Trial ID
NCT04424160
Start Date
September 15 2020
End Date
April 19 2021
Last Update
April 20 2021
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Acıbadem Maslak Hospital IVF Unit
Istanbul, Turkey (Türkiye), 34460