Status:
UNKNOWN
Influence of Manipulation of Oocytes and Embryos in Low Oxygen Tension on Assisted Reproduction Technology Outcome
Lead Sponsor:
The University of Hong Kong-Shenzhen Hospital
Conditions:
Embryo Hypoxia
Eligibility:
All Genders
Phase:
NA
Brief Summary
Nowadays, most assisted reproduction laboratories attempt to maintain as much as possible ex vivo culture conditions comparable to those in vivo. Various culturing condition such as temperature and pH...
Detailed Description
In the experimental group, oocyte pickup will be performed in a lower oxygen tension environment (5% oxygen, 89% nitrogen, 6% carbon dioxide); oocyte pickup will be performed in a special workstation ...
Eligibility Criteria
Inclusion
- all the couples undergoing conventional IVF cycle in the reproductive medicine center of the University of Hong Kong-Shenzhen Hospital
Exclusion
- Intracytoplasmic sperm injection (ICSI) cycle
- Preimplantation genetic testing (PGT) cycle
- cycle with fertilization failure ≥3
- cycle using sperm from percutaneous epididymal sperm aspiration (PESA)/testicular sperm extraction (TESE) or cryopreserved sperm
- cycle using cryopreserved oocyte
- cycle with no oocyte retrieved
Key Trial Info
Start Date :
March 22 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2023
Estimated Enrollment :
1160 Patients enrolled
Trial Details
Trial ID
NCT04424784
Start Date
March 22 2021
End Date
June 1 2023
Last Update
May 25 2021
Active Locations (1)
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1
Reproductive medicine center
Shenzhen, China