Status:

UNKNOWN

Prone Positioning on Admission for Hospitalized COVID-19 Pneumonia Protocol

Lead Sponsor:

Poudre Valley Health System

Conditions:

COVID-19

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

A pilot study to investigate the effects of the prone positioning (PP) on hospital patients diagnosed with COVID-19 pneumonia. Investigators that early self-proning may prevent intubation and improve...

Detailed Description

In hypoxic respiratory failure, placing patients in the prone position improves ventilation to perfusion matching, alveolar recruitment, and alveolar to arterial oxygen gradients. Specifically, in Acu...

Eligibility Criteria

Inclusion

  • Patients admitted to the hospital floor with primary diagnosis of confirmed COVID-19 pneumonia and respiratory failure requiring greater than or equal to 2 Liters(L) Nasal Cannula (NC) to maintain SpO2\>90%
  • Ability to independently change positions in bed
  • Able to tolerate prone positioning
  • Age greater than 18

Exclusion

  • ICU admission on arrival
  • Respiratory distress requiring immediate intubation
  • Respiratory Rate(RR)\>35/min, accessory respiratory muscle use (ex. speaking in short sentences), signs of respiratory muscle fatigue, altered mental status, or inability to protect airway
  • Chest or facial trauma, pneumothorax or other contraindication to prone positioning (i.e., spinal instability, recent abdominal surgery, pregnancy, etc)
  • Hemodynamically unstable
  • Heart Rate (HR)\>120 bpm, Systolic Blood Pressure (SBP)\<90 mmHg, Mean Arterial Pressure (MAP)\<65 mmHg or requirement for vasopressor
  • Nausea and vomiting
  • Pregnancy
  • Refusal or inability to tolerate initial prone positioning due to comfort

Key Trial Info

Start Date :

July 13 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 31 2022

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT04424797

Start Date

July 13 2020

End Date

July 31 2022

Last Update

April 25 2022

Active Locations (3)

Enter a location and click search to find clinical trials sorted by distance.

Page 1 of 1 (3 locations)

1

UCHealth Poudre Valley Hospital

Fort Collins, Colorado, United States, 80524

2

UCHealth Greeley Hospital

Greeley, Colorado, United States, 80634

3

UCHealth Medical Center of the Rockies

Loveland, Colorado, United States, 80538