Status:

COMPLETED

Predictive Value of Doppler RSI for Prediction of AKI in Septic Patients in ICU

Lead Sponsor:

Ain Shams University

Conditions:

Acute Kidney Injury

Sepsis

Eligibility:

All Genders

18-60 years

Brief Summary

Acute kidney injury (AKI) Diagnosis is based on rising creatinine. Intrarenal vasoconstriction occurs earlier and measuring flow resistance in the renal circulation (Renal Resistive Index (RRI)) could...

Detailed Description

Patients who have criteria of sepsis, with normal renal function on admission will undergo Renal Doppler Ultrasound examination to measure Renal resistive index. Patients will be divided into 2 group...

Eligibility Criteria

Inclusion

  • Patients who have criteria of sepsis on admission which include two or more of SIRS which include: (Temperature \>38°C or \<36°C, Heart rate \>90/min, Respiratory rate \>20/min or PaCO2 \<32mmHg (4.3kPa) and White blood cell count \>12000/mm3 or \<4000/mm3 or \>10% immature bands.) in addition to suspected or confirmed infection.
  • Patients who have normal renal function on admission.

Exclusion

  • Currently recovering from an AKI at the time of inclusion and Renal impairment on admission.
  • Patients with obstructive renal failure, renal artery stenosis were excluded from this study.
  • Patients on chemotherapy and/or radiotherapy.
  • Pregnancy.

Key Trial Info

Start Date :

July 1 2020

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

January 31 2021

Estimated Enrollment :

150 Patients enrolled

Trial Details

Trial ID

NCT04426032

Start Date

July 1 2020

End Date

January 31 2021

Last Update

July 20 2021

Active Locations (1)

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1

Ain Shams University Hospitals

Cairo, Egypt