Status:
COMPLETED
The Effect of Cyclosporin Before Cataract Surgery
Lead Sponsor:
Samsung Medical Center
Conditions:
Dry Eye Syndromes
Eligibility:
All Genders
21+ years
Phase:
PHASE4
Brief Summary
To evaluate the effect of cyclosporine eye drop before cataract surgery for the prevention of post cataract surgery dry eye syndrome.
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- 21+ adult men and women
- Those who are scheduled to undergo cataract surgery due to a diagnosis of cataract
- Corneal fluorescein staining score (Oxford) is II or less
- Preoperative MMP-9 positive
- Those who have not used the trial and the test (cyclosporine) for at least 1 month before surgery.
- Those who have voluntarily written consent to participate in this clinical trial
- Exclusion Criteria
- Those who have used systemic or topical cyclosporine within 4 weeks
- Use of eye drops for more than 4 weeks (disorders, allergies, eye inflammation / infection, etc.) other than the current dry eye syndromes
- Patients who have systemic or ocular disorders or conditions (eye surgery, trauma, disease) that can influence the results of this trial.
- Abnormal eyelid function
- An eye disease that can impair the function of the corneal sensation: herpes keratopathy, conjunctival wounds due to scarring conjunctivitis, pterygium, pinguecula, diabetic keratitis, keratoconus , corneal transplant status
- Patients with active eye infections
- Patients with conflicts with this clinical trial
- Pregnant and lactating mothers
- Patients who are determined to be inappropriate by other investigators
Exclusion
Key Trial Info
Start Date :
August 3 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 19 2022
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT04426240
Start Date
August 3 2020
End Date
April 19 2022
Last Update
May 13 2022
Active Locations (1)
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1
Samsung Medical Center
Seoul, South Korea