Status:

TERMINATED

Safety and Efficacy of Lenvatinib in Subjects With HCC Progression After First Line Treatment With Checkpoint Inhibitors

Lead Sponsor:

Humanity & Health Medical Group Limited

Collaborating Sponsors:

Beijing 302 Hospital

Kindai University Faculty of Medicine

Conditions:

Hepatocellular Carcinoma

Eligibility:

All Genders

18+ years

Brief Summary

The objective of this study is to evaluate the efficacy of lenvatinib in HCC subjects who have progressive disease after first line treatment with checkpoint inhibitors. Approximately 20 subjects wil...

Eligibility Criteria

Inclusion

  • Age ≥ 18 years old on the day of consent
  • Capable of understanding and complying with the protocol requirements and signed informed consent
  • Documented histological or cytological diagnosis of HCC
  • HCC progression after first line treatment with checkpoint inhibitors per RECIST 1.1

Exclusion

  • Fibrolamellar carcinoma or mixed hepatocellular cholangiocarcinoma
  • Prior TKI treatment

Key Trial Info

Start Date :

July 2 2022

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

September 30 2023

Estimated Enrollment :

17 Patients enrolled

Trial Details

Trial ID

NCT04428437

Start Date

July 2 2022

End Date

September 30 2023

Last Update

October 5 2023

Active Locations (1)

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1

Humanity & Health Clinical Trial Centre

Hong Kong, Hong Kong SAR, Hong Kong