Status:
WITHDRAWN
Biospecimen Procurement for Immunological Landscape Studies Following Hematopoietic Cell Transplantation
Lead Sponsor:
National Cancer Institute (NCI)
Conditions:
Hematopoietic Stem Cell Transplantation
Cell Transplantation
Eligibility:
All Genders
8+ years
Brief Summary
Background: Allogenic hematopoietic cell transplantation (HCT) is a procedure in which a person gets stem cells from a donor in order to treat their disease. Researchers want to collect samples from ...
Detailed Description
Background: * Allogenic Hematopoietic Cell Transplantation (HCT) is a potentially curative option for some patients with primary immunodeficiencies (PID) and hematological cancers. * HCT for PID look...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- Diagnosis of a hematologic malignancy, immunodeficiency or disorder of T-cell proliferation and/or dysregulation
- Have undergone or planning to undergo an allogenic hematopoietic cell transplantation
- Age greater than or equal to 8 years
- Additional inclusion criteria pertinent only for patients undergoing apheresis
- Hemoglobin greater than or equal to 8 mg/dL and platelet count \> 75 K/uL
- Weight greater than or equal to 48 kg
- Adequate venous access
- EXCLUSION CRITERIA:
- Active concomitant medical or psychological illnesses that may increase the risk to the subject
- Inability of subject or parent/legal guardian to provide informed consent
- Pregnant or breastfeeding women as some tests and procedures allowed are contraindicated in pregnancy (i.e., CT scans, administration of iodinated contrast)
Exclusion
Key Trial Info
Start Date :
June 5 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 17 2020
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT04428918
Start Date
June 5 2020
End Date
September 17 2020
Last Update
September 22 2020
Active Locations (1)
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1
National Institutes of Health Clinical Center
Bethesda, Maryland, United States, 20892