Status:

WITHDRAWN

Cryoablation for the Promotion of Local Tumor Infiltration in Patients With Mesothelioma

Lead Sponsor:

Jonsson Comprehensive Cancer Center

Conditions:

Mesothelioma

Eligibility:

All Genders

Phase:

NA

Brief Summary

This trial evaluates if cryoablation will stimulate a local immune response by cluster of differentiation 8 positive (CD8+) cells which are not present in ablation naive regions of the tumors in patie...

Detailed Description

PRIMARY OBJECTIVES: I. To evaluate the simple hypothesis that cryoablation of mesothelioma will promote local tumor infiltration by cytotoxic cluster of differentiation 8 positive (CD8+) cells that w...

Eligibility Criteria

Inclusion

  • Adults that have been identified at tumor board with high suspicion for mesothelioma and are anticipated to be surgical candidates, as determined/discussed at Mesothelioma Tumor Board

Exclusion

  • Patients that have a questionable diagnosis of mesothelioma (i.e. there are other potentially more likely considerations in the differential diagnosis) or in patients that would not be expected to be good surgical candidates

Key Trial Info

Start Date :

December 1 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2023

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT04429204

Start Date

December 1 2021

End Date

December 1 2023

Last Update

June 14 2021

Active Locations (1)

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Page 1 of 1 (1 locations)

1

UCLA / Jonsson Comprehensive Cancer Center

Los Angeles, California, United States, 90095