Status:
COMPLETED
Brain Gut Axis Changes After Bariatric Surgery and Their Relationship to Weight Loss
Lead Sponsor:
University of California, Los Angeles
Conditions:
Obesity
Bariatric Surgery Candidate
Eligibility:
FEMALE
18-55 years
Brief Summary
Assessing the changes in the brain-gut axis after weight loss surgery and their relationship with weight loss and changes in eating behaviors. Obese women undergoing weight loss surgery will be recru...
Detailed Description
Assessing the changes in the brain-gut axis after weight loss surgery and their relationship with weight loss and changes in eating behaviors. Obese women undergoing weight loss surgery will be recru...
Eligibility Criteria
Inclusion
- Women, age 18-55 years
- Eligible and approved for undergoing laparoscopic gastric bypass (LRYGB) or laparoscopic sleeve gastrectomy (LSG) following the Guidelines for Clinical application of Laparoscopic Bariatric Surgery by of American Gastrointestinal and Endoscopic Surgeons (SAGES)
- Right-handed
Exclusion
- Previous major gastrointestinal surgery including weight loss surgery (partial or complete resection of stomach and/or small bowel, Whipple procedure, etc)
- Use of medications known to affect hunger, satiety, or intestinal motility.
- Unwillingness or inability to give informed consent
- Any contraindication to undergo MRI
- Current or past alcohol or drug abuse problem or smoking
- Pregnancy, lactating or post partum less than 12 months
- Body weight at enrollment greater than 350 lbs.
- Current use of insulin and or insulin dependent diabetes
- Renal insufficiency, retinopathy, or neuropathy.
- Post menopausal (defined as no menses for 12 consecutive months)
Key Trial Info
Start Date :
February 15 2014
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
April 15 2021
Estimated Enrollment :
22 Patients enrolled
Trial Details
Trial ID
NCT04429386
Start Date
February 15 2014
End Date
April 15 2021
Last Update
August 16 2021
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